An artificial photosensitizer drug network for mitochondria-selective photodynamic therapy.
نویسندگان
چکیده
We report a new class of photosensitizer drug networks that can home into mitochondria and provide geospatial phototoxicity for tumors. We take advantage of the cleavable chemical network between the photosensitizer drug and poly(ethylene glycol), and find a significant increase in the efficiency of the multimeric drug network in mitochondria uptake and tumor inhibition.
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ورودعنوان ژورنال:
- Chemical communications
دوره 48 19 شماره
صفحات -
تاریخ انتشار 2012